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The Rising Demand for High-Potency ADC Payloads: Why the Supply Chain Is Being Reshaped in 2025Antibody–drug conjugates (ADCs) continue to reshape the oncology pipeline, driven by the pursuit of payloads that can deliver stronger potency, improved tumor selectivity, and reduced systemic toxicity. Although more than a decade has passed since the approval of the first ADC, payload development remains one of the fastest-moving components of the field. With growing interest in high-DAR...0 Reacties 0 aandelen 1K ViewsPlease log in to like, share and comment!
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From RA to Asthma: Preclinical Models Shaping the Future of ImmunotherapyThe pharmaceutical landscape is entering a phase of unprecedented focus on immune-mediated diseases, with research teams racing to develop treatments for conditions ranging from autoimmune disorders to chronic inflammatory diseases. The key to this progress is not just advanced molecular tools—it is also the strategic use of robust preclinical disease models that faithfully recapitulate...0 Reacties 0 aandelen 1K Views
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Why the Future of GI Research Is Happening Outside the BodyA new kind of gold rush is quietly reshaping drug discovery—and this time, the treasure is not buried in animal facilities or clinical trial databases, but preserved in living human gastrointestinal tissue. As pharmaceutical pipelines accelerate and regulatory expectations tighten, traditional in vivo models are showing their limits. Animal studies remain costly,...0 Reacties 0 aandelen 973 Views
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Boosting Antibody Success Rates with AI: Developability, Affinity, and BeyondThe biopharmaceutical industry is going through a silent but profound transformation. While headlines tend to focus on blockbuster drugs or billion-dollar mergers, another movement is gathering momentum beneath the surface—one powered not by laboratory throughput alone, but by algorithmic intelligence. Antibody engineering, once defined by trial-and-error approaches and lengthy...0 Reacties 0 aandelen 1K Views
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What the Microbiome Gold Rush Means for Drug DevelopersA new kind of gold rush is underway in the life sciences—but this time, the treasure isn't hidden in exotic animal models or rare tissues. Instead, it lies deep within the human gut. As microbiome science moves from descriptive studies to mechanism-driven therapeutic development, demand for well-characterized probiotic strains has surged dramatically. What was once an...0 Reacties 0 aandelen 1K Views
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Beyond Herbal Extracts: Why Centella asiatica Exosomes Are the Future of Natural SkincareCentella asiatica, also known as Gotu Kola, has been used in traditional medicine for centuries to heal wounds, rejuvenate skin, and calm inflammation. Modern biotechnology is now revealing that its therapeutic power may go far beyond triterpenoids and saponins. Recent studies have identified a new bioactive component within this herb—plant-derived exosomes, nanosized vesicles that...0 Reacties 0 aandelen 1K Views
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From Inflammation to Immune Evasion: The Central Role of IL-6 and BCL2Cancer development is not just about uncontrolled cell growth; it’s a complex interplay between the tumor cells, their surrounding environment, and the body’s immune system. Three key factors — Interleukin-6 (IL-6), B-cell lymphoma 2 (BCL2), and natural killer (NK) cells — are central to this dynamic process, each influencing tumor progression and the body’s...0 Reacties 0 aandelen 1K Views
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Next-Generation Immunoassay Platforms: Bridging Precision and PerformanceIn vitro diagnostics (IVD) have become the cornerstone of modern medical decision-making. Among the vast array of analytical technologies, immunoassays stand out for their high specificity, sensitivity, and adaptability. Over the past few decades, continuous technological refinement—from colorimetric to chemiluminescent detection—has redefined how clinicians and researchers...0 Reacties 0 aandelen 1K Views
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Teaching Liver Cancer Cells to Self-Destruct: A New Frontier in Oncology ResearchA quiet revolution is unfolding in cancer research laboratories—and it has nothing to do with blockbuster drugs or billion-dollar acquisitions. Instead, it centers on a deceptively simple idea: what if cancer cells could be engineered to destroy themselves on command? In liver cancer research, this concept of "self-destruction" is rapidly gaining traction. As hepatocellular...0 Reacties 0 aandelen 1K Views
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